Comparison 1. S‐Adenosylmethionine versus placebo.
Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
---|---|---|---|---|
1 Pain | 2 | 533 | Std. Mean Difference (Random, 95% CI) | ‐0.17 [‐0.35, 0.01] |
2 Function | 3 | 542 | Std. Mean Difference (Random, 95% CI) | 0.02 [‐0.68, 0.71] |
3 Number of patients experiencing any adverse event | 4 | 623 | Risk Ratio (IV, Random, 95% CI) | 1.27 [0.94, 1.71] |
4 Number of patients who withdrew because of adverse events | 4 | 656 | Risk Ratio (IV, Random, 95% CI) | 0.94 [0.48, 1.86] |