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. 2020 Mar 9;16(3):e9275. doi: 10.15252/msb.20199275

Figure 1. tRNA quantification and modifications from small RNA‐seq data.

Figure 1

  1. Schematic pipeline for accurate mapping of tRNA reads.
  2. Correlations between tRNA quantifications by small RNA‐seq and Hydro‐tRNAseq of matching (correlations within the same cell line) versus non‐matching (different cell lines) samples. Center values represent the median. The P‐value corresponds to a one‐tailed Wilcoxon rank‐sum test, with n matching = 9 and n non‐matching = 63.
  3. Overlap of the detected tRNA modifications upon variant calling by both methods.
  4. The TCGA network contains small RNA‐seq data alongside mRNA‐seq, DNA methylation arrays, non‐targeted proteomics, and copy number alteration quantification comprising 17 tissues.

Source data are available online for this figure.