Figure EV5. Differential expression of tRNAs between healthy and tumor samples across 22 cancer types, related to Fig 4 .

1. tRNA abundance is measured as relative anticodon abundance, and the fold change is log₂(RAA_Tumor/RAA_Healthy). Refer to Table EV4 for full cancer type names and number of samples.
2. Absolute tRNA differential abundance by log₂(tRNA_Tumor/tRNA_Healthy). Only significant differences are colored, which are determined using a two‐tailed Wilcoxon rank‐sum test and corrected for multiple testing by FDR.