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Single-agent or combination drug and antibody nanoparticle delivery systems. Preparation of the TfR-targeted combination CPT/Herceptin nanoparticle (A), TfR-targeted CPT nanoparticle (B), and TfR-targeted Herceptin nanoparticle (C) formulations. w ~ 82 for 3.4 kDa PEG; x ~ 20 for material used in this study; y ~ 84 for 3.5 kDa PEG; z ~ 120 for 5 kDa PEG.
