Spitzer 1982.
Methods | Allocation concealment ‐ can't tell. Randomization into blocks of two in order to stratify according to birth weight. The intervention was randomized for the first infant entering into a birth weight category and the next infant received the other intervention. Blinding of intervention ‐ no. Completeness of follow‐up ‐ no, as 14 additional infants were excluded because of early death or because they required ventilation for <48 hours. Blinding of outcome ‐ no. | |
Participants | Analysis resulted in 86 newborn infants requiring ventilation for >48 hours. Stratified into weight groups >3000 gram and 3000 gram and less divided into 500 grams groups | |
Interventions | Endotracheal intubation by either nasal or oral route | |
Outcomes | Tube blockage Pneumothorax Post extubation atelectasis reported by weight groups Re‐intubation Local trauma | |
Notes | The focus of the study was on post‐extubation atelectasis | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |