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. Author manuscript; available in PMC: 2020 Mar 9.
Published in final edited form as: Prostate. 2017 Mar 1;77(7):749–764. doi: 10.1002/pros.23311

TABLE I.

Basic Characteristics of the Newly Developed mAbs

mAb Isotype Epitope Residuesa Speciesb Experimental usec
1A11 IgG1/κ Linear 271–288 Human WB, ICC, IHC, ELISA
3F11 IgG1/κ Linear 226–243 Human, mouse, rat, pig, dog WB, ICC, IHC, ELISA
5B1 IgG1/κ Conformational n.d. Human IF, ICC, IHC, ELISA, FC, in vivo
5D3 IgG1/κ Conformational n.d. Human IF, ICC, IHC, ELISA, FC, in vivo
a

Residues of human PSMA recognized by a given mAb.

b

PSMA orthologs recognized by a given mAb.

c

WB, Western blotting; ELISA, enzyme-linked immunosorbent assay; IHC, immunohistochemistry; ICC, immunocytochemistry; FC, flow cytometry; IF, immunofluorescence.