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. 2020 Mar 4;16:181–187. doi: 10.2147/TCRM.S192392

Table 1.

Inclusion Characteristics of Patients in Dupilumab Studies

Baseline Characteristics Considerations
Failing > 500 µg of fluticasone propionate Inclusion criterion for all of the phase 3 asthma trials
Failing an additional controller medication Inclusion criterion for all of the phase 3 asthma trials
12% reversibility in FEV1 at baseline Inclusion criterion for moderate-to-severe trials
Asthma Control Questionnaire > 1.5 Inclusion criterion for moderate-to-severe trials
Oral glucocorticoid dependent asthma Inclusion criteria for severe steroid dependent trial

Abbreviation: FEV1, forced expiratory volume in one second.