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. Author manuscript; available in PMC: 2020 Mar 9.
Published in final edited form as: Chem Res Toxicol. 2018 Aug 2;31(8):762–771. doi: 10.1021/acs.chemrestox.8b00102

Figure 12.

Figure 12.

Syn or anti additions of dA to reduced DMC depend on the nature of the adjacent 3’ base. Anti addition is favored at 3’-AG and 3’-AA. At 3’-AT and 3’-AC syn addition is favored.