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. Author manuscript; available in PMC: 2020 Mar 9.
Published in final edited form as: J Proteomics Bioinform. 2019 Aug 13;12(6):96–103. doi: 10.35248/0974-276x.19.12.502

Figure 6.

Figure 6.

Metabolite levels are differentially affected by irradiation depending upon cell line. Cells were irradiated (6 Gy) and collected 24 h after for analysis via mass spectrometry. A) Adenylate energy charges were maintained near pre-irradiated levels. B) Energy metabolite concentrations (p<0.0001) and C) amino acid concentrations (p<0.0001) were shown to increase significantly for U251 cells after radiation. D) Glutamine/glutamate ratios were similar to pre-irradiated levels. Values represent the mean ± standard deviation for 3 independent trials. P values are for comparison to irradiated NSC11 cells (* p<0.05, **** p<0.0001).