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. 2020 Feb 17;11:354–369. doi: 10.3762/bjnano.11.26

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Copyright © 2020, Kandasamy et al.

This is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited.

The license is subject to the Beilstein Journal of Nanotechnology terms and conditions: (https://www.beilstein-journals.org/bjnano/terms)

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(A) Migration of A549 cells analyzed using Boyden chamber assay 48 h after treatment. a: Control; b: free siRNA; c: blank polymer nanoparticles; d: polyplex with scrambled siRNA; e: polyplex with VEGF siRNA. VEGF silencing slows down the migration of A549 cells. The cells were stained using 0.5% crystal violet for visualization and images were taken using phase-contrast microscopy. The scale bars represent 50 μm. (B) Migration of the A549 cells 48 h after treatment, *p < 0.05 vs control.