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. 2001 Oct 23;2001(4):CD000369. doi: 10.1002/14651858.CD000369

Calleri 1998.

Methods Randomisation: yes 
 Blinding: no 
 Intention to treat: yes Methodological score: 8
Participants ‐ Patients with acute hepatitis C 
 ‐ n = 40 
 ‐ Arms (IFN/C): 20/20 
 ‐ RNA + at entry: no data available (NDA) 
 ‐ Excluded: 0/0 
 ‐ Mean age (y): 29/29 
 ‐ Male (%): 85/85 
 ‐ Transfusion (%): 5/5 
 ‐ Drug abuse (%): 65/65 
 ‐ Genotype: NDA 
 ‐ Mean disease duration (wk): NDA
Interventions ‐ Schedule: 
 Control: no intervention 
 Experimental: IFN beta 3 MU/day x 5 d; 3 MU tiw x 3 wk 
 ‐Follow‐up (F/U): 22 mo
Outcomes ‐ Biochemical ETR and SR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear