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. 2001 Oct 23;2001(4):CD000369. doi: 10.1002/14651858.CD000369

Hwang 1994.

Methods Randomisation: yes 
 Blinding: no 
 Intention to treat: yes Methodological score: 13
Participants ‐ Patients with acute hepatitis C 
 ‐ n = 33 
 ‐ Arms (IFN/C): 16/17 
 ‐ RNA + at entry: 16/17 
 ‐ Excluded: 0/1 
 ‐ Mean age (y): 53/55 
 ‐ Male (%): 75/71 
 ‐ Transfusion (%): 100/100 
 ‐ Drug abuse (%): 0/0 
 ‐ Genotype: G1 54%, G2 30%, Other 15% 
 ‐ Mean disease duration (wk): 9/10
Interventions ‐ Schedule: 
 Control: no intervention 
 Experimental: IFN alpha‐2b 3 MU tiw x 3 mo 
 ‐F/U: 12 mo
Outcomes ‐ Biochemical ETR and SR 
 ‐ Virologic ETR and SR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear