Omata 1991.

Methods	Randomisation: yes Blinding: no Intention to treat: yes Methodological score: 12
Participants	‐ Patients with acute hepatitis C ‐ n = 25 ‐ Arms (IFN/C): 11/14 ‐ RNA + at entry: 10/12 ‐ Excluded: 0/0 ‐ Mean age (y): 40/38 ‐ Male (%): 44/50 ‐ Transfusion (%): 88/71 ‐ Drug abuse (%): NDA ‐ Genotype: NDA ‐ Mean disease duration: NDA
Interventions	‐ Schedule: Control: no intervention Experimental: IFN beta 3 MU/d x 5 days; 3 MU tiw x 3 wk ‐ F/U: 12 mo
Outcomes	‐ Biochemical ETR ‐ Virologic ETR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear