Degos 1998.

Methods	Allocation concealment: unclear. Blinding: no. Intention to treat: yes. Methodological score: 16.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 124/122 Excluded: 12/14 Mean age: 37/37 % males: 68/60 % transfusion: 33/28 % drug abuse: 31/32 % cirrhosis: 0/0 Genotypes: G1 (52/56), G2,3 (39/36), other (9/8) Disease duration: 11/12
Interventions	Experimental 1: Alfa‐2a IFN 6 MU/d x 12d; 6 MU TIW x 22 wk; 3 MU TIW x 24 wk Experimental 2: Alfa‐2a IFN 3 MU TIW x 24 wk Follow‐up: 6 mo
Outcomes	‐ biochemical ETR and SR ‐ virologic SR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear