Diodati 1994.

Methods	Allocation concealment: unclear. Blinding: no. Intention to treat: yes. Methodological score: 13.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 30/30 Excluded: 1/5 Mean age: 49/55 % males: 77/43 % transfusion: 23/23 % drug abuse: NDA % cirrhosis: 50/40 Genotypes: NDA Disease duration: 8/7
Interventions	Experimental: Alfa‐2a IFN 6 MU TIW x 1mo; 3 MU x 3 mo; 1 MU TIW x 8 mo Control: no intervention Follow‐up: 6 mo
Outcomes	‐ biochemical ETR and SR ‐ liver histology
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear