Gomez‐Rubio 1990.

Methods	Allocation concealment: unclear. Blinding: no. Intention to treat: yes. Methodological score: 12.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 15/15 Excluded: 2/0 Mean age: 41/40 % males: 60/53 % transfusion: 60/73 % drug abuse: 7/7 % cirrhosis: 27/7 Genotypes: NDA Disease duration: 7/8
Interventions	Experimental: Alfa‐2b IFN 5 MU TIW x 2 mo; 1.5 MU TIW x 16 mo Control: no intervention Follow‐up: 6 mo
Outcomes	‐ biochemical ETR and SR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear