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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Ikeda 1998.

Methods Allocation concealment: unclear. 
 Blinding: no. 
 Intention to treat: no. 
 Methodological score: 10.
Participants NAIVE PATIENTS WITH CHRONIC HEPATITIS C AND CIRRHOSIS 
 Arms: 14/15 
 Excluded: 1/0 
 Mean age : 52/57 
 % males: NDA 
 % transfusion: NDA 
 % drug abuse: NDA 
 % cirrhosis: 100/100 
 Genotypes : G2 (100/100%) 
 Disease duration: NDA
Interventions Experimental: Alfa‐2a IFN 9 MU TIW x 6 mo
Control: no intervention
Follow‐up: 3 mo
Outcomes ‐ biochemical SR 
 ‐ virologic ETR and SR 
 ‐ incidence of hepatocellular carcinoma
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear