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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Makris 1991.

Methods Allocation concealment: unclear. 
 Blinding: no. 
 Intention to treat: yes. 
 Methodological score: 12.
Participants NAIVE HEMOPHILIACS WITH CHRONIC HEPATITIS C 
 Arms: 10/8 
 Excluded: 1/0 
 Mean age: 38/38 
 % males: 100/100 
 % transfusion: 100/100 
 % drug abuse: 0/0 
 % cirrhosis: 10/12 
 Genotypes: NDA 
 Disease duration: NDA
Interventions Experimental: Alfa‐2b IFN 1 MU TIW x 1 mo; 2 MU TIW x 1 mo; 3 MU TIW x 10 mo
Control: no intervention
Follow‐up: 15 mo
Outcomes ‐ biochemical ETR 
 ‐ liver histology
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear