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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Marcellin 1991.

Methods Allocation concealment: unclear. 
 Blinding: no. 
 Intention to treat: no. 
 Methodological score: 12.
Participants NAIVE PATIENTS WITH CHRONIC HEPATITIS C 
 Arms: 18/18 
 Excluded: 2/0 
 Mean age: 42/41 
 % males: 67/50 
 % transfusion: 50/56 
 % drug abuse: 28/28 
 % cirrhosis: 17/11 
 Genotypes: NDA 
 Disease duration: 4/4
Interventions Experimental: Alfa‐2b IFN 3 MU TIW x 6 mo
Control: no intervention
Follow‐up: 6 mo
Outcomes ‐ biochemical ETR and SR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear