Marcellin 1995.

Methods	Allocation concealment: adequate (sealed envelopes). Blinding: no. Intention to treat: no. Methodological score: 15.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 50/25 Excluded: 7/1 Mean age: 43/44 % males: 53/68 % transfusion: 62/68 % drug abuse: 32/32 % cirrhosis: 8/20 Genotypes: NDA Disease duration: 12/12
Interventions	Experimental 1: AlFa‐2b IFN 3 MU TIW x 8 wk; 5 MU TIW x 8 wk; 10 MU TIW x 8 wk Experimental 2: Alfa‐2b IFN 3 MU TIW x 6 mo Follow‐up: 6 mo
Outcomes	‐ biochemical ETR and SR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate