Matsumoto 1994.

Methods	Allocation concealment: unclear. Blinding: no. Intention to treat: yes. Methodological score: 8.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 12/12 Excluded: 0/0 Mean age: 48/45 % males: 75/74 % transfusion: 25/33 % drug abuse: NDA % cirrhosis: NDA Genotypes: G1 (75/75%), G2(25/25%) Disease duration: NDA
Interventions	Experimental 1: Alfa‐2a IFN 9 MU/day x 2 wk; 9 MU TIW x 6 mo Experimental 2: Alfa‐2a IFN 3 MU/day x 2 wk; 3 MU x 6 mo Follow‐up: 6 mo
Outcomes	‐ biochemical SR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear