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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Mazella 1994.

Methods Allocation concealment: adequate (sealed envelopes). 
 Blinding: no. 
 Intention to treat: no. 
 Methodological score: 13.
Participants NAIVE PATIENTS WITH CHRONIC HEPATITIS C 
 Arms: 30/30 
 Excluded: 1/0 
 Mean age: 45/48 
 % males: 68/50 
 % transfusion: NDA 
 % drug abuse: NDA 
 % cirrhosis: NDA 
 Genotypes: NDA 
 Disease duration: 5/5
Interventions Experimental: Alfa‐n‐1 IFN 3 MU TIW x 12 mo
Control: no intervention
Follow‐up: 16 mo
Outcomes ‐ biochemical ETR and SR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate