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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Rumi 1995.

Methods Allocation concealment: unclear. 
 Blinding: no. 
 Intention to treat: no. 
 Methodological score: 16.
Participants NAIVE PATIENTS WITH CHRONIC HEPATITIS C 
 Arms: 38/36 
 Excluded: 3/4 
 Mean age: 48 
 % males: 63 
 % transfusion: NDA 
 % drug abuse: NDA 
 % cirrhosis: 31 
 Genotypes: NDA 
 Disease duration: NDA
Interventions Experimental: Alfa‐2a IFN 6MU TIW x 2 mo; 3MU TIW x 10 mo
Control: no intervention
Follow‐up: 12 mo
Outcomes ‐ biochemical ETR and SR 
 ‐ virologic ETR and SR 
 ‐ liver histology
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear