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. 2002 Apr 22;2002(2):CD000370. doi: 10.1002/14651858.CD000370

Saracco 1990.

Methods Allocation concealment: unclear. 
 Blinding: no. 
 Intention to treat: no. 
 Methodological score: 12.
Participants NAIVE PATIENTS WITH CHRONIC HEPATITIS C 
 Arms: 26/25 
 Excluded: 3/5 
 Mean age: 48/47 
 % males: 62/60 
 % transfusion: 46/48 
 % drug abuse: 54/52 
 % cirrhosis: 50/24 
 Genotypes: NDA 
 Disease duration: NDA
Interventions Experimental: IFN 3 MU TIW x 6 mo
Control: no intervention
Follow‐up: 6 mo
Outcomes ‐ biochemical ETR and SR 
 ‐ liver histology
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear