Shiratori 1997.

Methods	Allocation concealment: unclear. Blinding: no. Intention to treat: yes. Methodological score: 17.
Participants	NAIVE PATIENTS WITH CHRONIC HEPATITIS C Arms: 133/139 Excluded: 0/0 Mean age: 47/53 % males: 73/62 % transfusion: 46/51 % drug abuse: NDA % cirrhosis: 0/0 Genotypes: G1 (81/74%), G2 (19/26%) Disease duration: NDA
Interventions	Experimental 1: Alfa‐nat IFN 9 MU TIW x 6 mo Experimental 2: Alfa‐nat IFN 6 MU TIW x 6 mo Follow‐up: 12 mo
Outcomes	‐ virologic ETR and SR
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear