Fig. 5.

Characteristics of printed constructs based on HA modified inks. (A) (i) Chemical structure of methacrylated HA obtained by reacting HA with methacrylic anhydride in an aqueous environment and (ii) printability of methacrylated hyaluronic acid (MeHA) at different concentrations (scale bar ​= ​500 ​μm). The best printability was attained at MeHA concentration of 3%. Reproduced from Poldervaart et al. [71] (B) Compressive elastic properties of HA methylcellulose as a function of methylcellulose at different time points. Reproduced from Law et al. [74] with permission from Elsevier. (C) Comparing cell response in two different culture media (expansion and adipo), for cells seeded on either 2D surface or encapsulated in alginate, HA, or in collagen gels. Promoted cell differentiation and proliferation were seen in HA and collagen I gels (scale bar ​= ​50 ​μm; nuclei, actin filaments, and lipid droplets were shown in blue, green, and red, respectively). Reproduced from Henriksson et al. [75] with permission from IOP Publishing Copyright 2016. HA, hyaluronan.