Date	Event	Description
12 August 2012	New citation required but conclusions have not changed	Pediatric data has been incorporated into the update.
19 April 2011	New search has been performed	Addition of seven new trials to the systematic review and meta‐analysis, published after the original 2001 review.
8 November 2009	Amended	Published notes added.
23 September 2008	Amended	Converted to new review format.
1 July 2005	New search has been performed	The date of the latest search for evidence to the review is 01/07/2005, no new studies were identified. In a previous update on 27/09/02 we found one new study which we included as published data of the study N138 (Ben‐Menachem et al. Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory seizures: a multicenter, double‐blind, responder‐selected study evaluating monotherapy. European Levetiracetam Study Group. Epilepsia 2000;41(10):1276‐83). One study was also added to the 'Studies awaiting assessment' section (Boon P et al. Dose‐response effect of levetiracetam 1000 and 2000 mg/day in partial epilepsy. Epilepsy Research 2002;48(1‐2): 77‐89) ‐ This will be assessed for inclusion at a later date.