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. 2020 Mar 3;15:501–514. doi: 10.2147/COPD.S231317

Table 3.

The Relative Risk (95% CIs) of Asthma Admissions with an Increase of 10 µg/M3 in PM2.5, NO, NO2 and SO2 According to Single Lag, Adjusted Unconstrained and Constrained DLM Modelsa

Respondents Pollutant Lag Lag Terms Model One at Time RR (95% CI) Adjusted Unconstrained DLM RR (95% CI) Adjusted Constrained DLM RR(95% CI)
Total PM2.5 0 1.002 (1.000–1.004) 1.000 (0.997–1.003) 1.001 (0.998–1.003)
1 1.000 (0.997–1.003) 0.998 (0.995–1.002) 1.002 (1.000–1.004)
2 1.004 (1.002–1.006) 1.004 (1.002–1.007)* 1.002 (1.000–1.004)
3 1.002 (0.999–1.004) 1.003 (1.000–1.006) 1.000 (0.999–1.001)
4 1.000 (0.997–1.003) 0.997 (0.994–1.001) 1.000 (0.999–1.001)
5 1.000 (0.997–1.003) 0.999 (0.996–1.002) 1.000 (0.999–1.001)
6 1.002 (0.999–1.004) 1.003 (1.000–1.006) 1.000 (0.999–1.001)
7 1.000 (0.997–1.003) 0.998 (0.995–1.002) 1.000 (0.999–1.001)
NO 0 0.999 (0.998–1.001) 0.984 (0.966–1.003) 0.993 (0.975–1.010)
1 1.000 (0.999–1.002) 1.025 (1.005–1.045)* 1.000 (0.989–1.010)
2 0.999 (0.997–1.001) 0.973 (0.952–0.994) 1.000 (0.989–1.010)
3 1.001 (0.999–1.002) 1.009 (0.989–1.030) 1.003 (0.997–1.009)
4 1.001 (1.000–1.003) 1.016 (0.997–1.035) 1.003 (0.997–1.009)
5 1.000 (0.998–1.002) 0.988 (0.968–1.008) 1.003 (0.997–1.009)
6 1.001 (0.999–1.002) 1.014 (0.994–1.034) 1.003 (0.997–1.009)
7 1.000 (0.998–1.002) 0.992 (0.974–1.010) 1.003 (0.997–1.009)
NO2 0 0.994 (0.971–1.016) 0.981 (0.953–1.009) 0.995 (0.970–1.022)
1 1.000 (0.978–1.022) 1.040 (1.008–1.074)* 0.996 (0.981–1.011)
2 0.975 (0.953–0.999) 0.940 (0.908–0.973) 0.996 (0.981–1.011)
3 1.008 (0.987–1.030) 1.033 (1.001–1.067)* 1.000 (0.993–1.006)
4 1.010 (0.988–1.031) 1.025 (0.993–1.057) 1.000 (0.993–1.006)
5 0.981 (0.959–1.004) 0.955 (0.923–0.988) 1.000 (0.993–1.006)
6 0.997 (0.975–1.019) 1.008 (0.975–1.042) 1.000 (0.993–1.006)
7 1.002 (0.981–1.024) 1.002 (0.976–1.030) 1.000 (0.993–1.006)
Male PM2.5 0 1.003 (1.000–1.006) 1.002 (0.999–1.006) 1.002 (0.999–1.006)
1 1.001 (0.998–1.004) 1.000 (0.996–1.004) 1.002 (0.999–1.004)
2 1.004 (1.001–1.006) 1.004 (1.000–1.007) 1.002 (0.999–1.004)
3 1.002 (0.998–1.005) 1.002 (0.998–1.006) 1.000 (0.999–1.001)
4 0.997 (0.993–1.002) 0.993 (0.987–0.999) 1.000 (0.999–1.001)
5 1.002 (0.999–1.005) 1.001 (0.997–1.006) 1.000 (0.999–1.001)
6 1.004 (1.001–1.007) 1.004 (1.001–1.008)* 1.000 (0.999–1.001)
7 1.000 (0.996–1.004) 0.997 (0.992–1.002) 1.000 (0.999–1.001)
NO2 0 1.010 (0.979–1.041) 0.985 (0.947–1.024) 1.000 (0.965–1.037)
1 1.024 (0.995–1.054) 1.052 (1.007–1.099)* 1.007 (0.987–1.028)
2 0.998 (0.968–1.030) 0.949 (0.904–0.996) 1.007 (0.987–1.028)
3 1.021 (0.992–1.051) 1.045 (0.999–1.093) 1.002 (0.993–1.011)
4 1.013 (0.984–1.044) 1.014 (0.968–1.062) 1.002 (0.993–1.011)
5 0.983 (0.952–1.016) 0.960 (0.914–1.008) 1.002 (0.993–1.011)
6 1.005 (0.974–1.036) 1.018 (0.970–1.068) 1.002 (0.993–1.011)
7 1.004 (0.973–1.036) 0.998 (0.959–1.039) 1.002 (0.993–1.011)
Female PM2.5 0 1.000 (0.996–1.004) 0.997 (0.993–1.002) 0.998 (0.994–1.002)
1 0.996 (0.991–1.002) 0.994 (0.988–1.000) 1.002 (1.000–1.005)
2 1.004 (1.001–1.006) 1.006 (1.002–1.010)* 1.002 (1.000–1.005)
3 1.002 (0.999–1.005) 1.004 (0.999–1.008) 1.000 (0.998–1.001)
4 1.002 (0.998–1.005) 1.002 (0.998–1.007) 1.000 (0.998–1.001)
5 0.994 (0.988–1.000) 0.993 (0.986–1.000) 1.000 (0.998–1.001)
6 0.998 (0.993–1.003) 0.999 (0.993–1.004) 1.000 (0.998–1.001)
7 1.001 (0.997–1.004) 1.000 (0.996–1.005) 1.000 (0.998–1.001)
NO 0 0.998 (0.996–1.001) 0.969 (0.944–0.994) 0.983 (0.960–1.007)
1 1.000 (0.998–1.002) 1.041 (1.016–1.067)* 0.999 (0.986–1.013)
2 0.998 (0.995–1.000) 0.954 (0.927–0.982) 0.999 (0.986–1.013)
3 1.001 (0.999–1.003) 1.020 (0.994–1.046) 1.003 (0.996–1.010)
4 1.001 (0.999–1.003) 1.006 (0.982–1.032) 1.003 (0.996–1.010)
5 1.001 (0.999–1.003) 0.995 (0.969–1.021) 1.003 (0.996–1.010)
6 1.001 (0.999–1.003) 1.008 (0.983–1.033) 1.003 (0.996–1.010)
7 1.000 (0.998–1.002) 0.998 (0.975–1.021) 1.003 (0.996–1.010)
≤60 years PM2.5 0 1.000 (0.997–1.003) 0.999 (0.995–1.002) 0.999 (0.995–1.002)
1 1.000 (0.996–1.003) 0.999 (0.995–1.003) 1.002 (1.000–1.004)
2 1.003 (1.001–1.005) 1.005 (1.001–1.008)* 1.002 (1.000–1.004)
3 1.002 (0.999–1.005) 1.004 (1.000–1.007) 1.000 (0.999–1.001)
4 0.999 (0.995–1.003) 0.996 (0.992–1.000) 1.000 (0.999–1.001)
5 1.000 (0.997–1.003) 0.998 (0.995–1.002) 1.000 (0.999–1.001)
6 1.002 (0.999–1.005) 1.003 (0.999–1.006) 1.000 (0.999–1.001)
7 1.001 (0.998–1.004) 1.000 (0.996–1.003) 1.000 (0.999–1.001)
NO2 0 0.993 (0.968–1.019) 0.981 (0.950–1.013) 0.997 (0.968–1.027)
1 0.996 (0.971–1.022) 1.042 (1.005–1.081)* 0.993 (0.976–1.011)
2 0.971 (0.945–0.997) 0.929 (0.893–0.967) 0.993 (0.976–1.011)
3 1.010 (0.986–1.035) 1.046 (1.009–1.084) 0.999 (0.992–1.007)
4 1.008 (0.984–1.033) 1.017 (0.981–1.054) 0.999 (0.992–1.007)
5 0.977 (0.951–1.003) 0.958 (0.922–0.996) 0.999 (0.992–1.007)
6 0.990 (0.965–1.016) 1.000 (0.963–1.038) 0.999 (0.992–1.007)
7 0.997 (0.973–1.022) 1.005 (0.975–1.037) 0.999 (0.992–1.007)
>60 years PM2.5 0 1.006 (1.003–1.009) 1.005 (1.001–1.009)* 1.006 (1.002–1.009)
1 0.999 (0.993–1.005) 0.993 (0.983–1.002) 1.000 (0.997–1.004)
2 1.005 (1.002–1.009) 1.003 (0.998–1.008) 1.000 (0.997–1.004)
3 1.001 (0.996–1.006) 1.001 (0.994–1.009) 1.000 (0.998–1.002)
4 1.001 (0.996–1.006) 1.001 (0.994–1.007) 1.000 (0.998–1.002)
5 0.998 (0.992–1.005) 1.000 (0.993–1.008) 1.000 (0.998–1.002)
6 0.999 (0.993–1.005) 1.002 (0.996–1.009) 1.000 (0.998–1.002)
7 0.992 (0.982–1.002) 0.990 (0.980–1.001) 1.000 (0.998–1.002)
NO 0 0.998 (0.995–1.002) 0.959 (0.919–1.000) 0.979 (0.942–1.018)
1 1.002 (0.999–1.005) 1.065 (1.026–1.106)* 1.012 (0.993–1.031)
2 1.000 (0.996–1.003) 0.946 (0.904–0.990) 1.012 (0.993–1.031)
3 1.004 (1.002–1.007) 1.057 (1.019–1.095)* 1.010 (1.000–1.021)
4 1.002 (0.999–1.005) 1.015 (0.976–1.055) 1.010 (1.000–1.021)
5 1.000 (0.997–1.004) 0.974 (0.931–1.018) 1.010 (1.000–1.021)
6 1.001 (0.998–1.005) 1.020 (0.978–1.064) 1.010 (1.000–1.021)
7 1.002 (0.999–1.005) 1.009 (0.974–1.046) 1.010 (1.000–1.021)
NO2 0 1.006 (0.965–1.049) 0.982 (0.931–1.037) 0.996 (0.949–1.045)
1 1.019 (0.978–1.060) 1.042 (0.980–1.108) 1.005 (0.978–1.033)
2 0.996 (0.953–1.040) 0.974 (0.913–1.040) 1.005 (0.978–1.033)
3 1.006 (0.964–1.049) 0.986 (0.924–1.053) 1.005 (0.993–1.016)
4 1.026 (0.988–1.067) 1.069 (1.004–1.137)* 1.005 (0.993–1.016)
5 1.001 (0.959–1.044) 0.950 (0.891–1.012) 1.005 (0.993–1.016)
6 1.019 (0.980–1.061) 1.015 (0.952–1.081) 1.005 (0.993–1.016)
7 1.029 (0.992–1.068) 1.009 (0.959–1.062) 1.005 (0.993–1.016)
SO2 0 1.012 (0.972–1.054) 0.993 (0.936–1.053) 0.986 (0.937–1.038)
1 1.028 (0.992–1.066) 1.005 (0.942–1.072) 1.031 (1.006–1.057)
2 1.049 (1.014–1.085) 1.069 (1.017–1.124)* 1.031 (1.006–1.057)
3 1.010 (0.969–1.053) 0.986 (0.924–1.052) 1.003 (0.990–1.016)
4 1.000 (0.956–1.045) 0.958 (0.887–1.035) 1.003 (0.990–1.016)
5 1.028 (0.991–1.066) 1.040 (0.978–1.106) 1.003 (0.990–1.016)
6 1.032 (0.997–1.069) 1.026 (0.968–1.088) 1.003 (0.990–1.016)
7 1.012 (0.971–1.054) 0.985 (0.931–1.041) 1.003 (0.990–1.016)

Notes: *Statistically significant. aAdjusted for trend, seasonality, temperature, relative humidity, weekdays, and holidays.