Figure 1.

PDCD4 inhibits p62 expression and suppressed cell proliferation in human lung cancer cells. Three lung cancer cell lines were transiently transfected with PDCD4 wild-type and analyzed by qRT-PCR and western blot. A. PDCD4 and p62 protein expression levels. B. PDCD4 and p62 mRNA levels. C. Phase-contrast images of the control (left), vector control (middle) and PDCD4 overexpression cells (right) at 48 h after PDCD4 wild-type treatment. D. PDCD4 wild-type transfected into A549 (left panel) and H460 cells (right panel) and after 48 h, cell growth were analyzed by WST-8 assay.