Table 2.
Effects of SEAE on serum TG, TC, LDL-C, and HDL-C in high-fat- and vitamin D3-induced rodent model of atherosclerosis
| Group | n | TG (mmol/L) | TC (mmol/L) | LDL-C (mmol/L) | HDL-C (mmol/L) |
|---|---|---|---|---|---|
| Blank control | 10 | 0.48±0.21 | 1.82±0.32 | 0.69±0.32 | 0.87±0.30 |
| AS Model | 8 | 1.25±0.65* | 3.77±1.05** | 2.73±1.18* | 0.91±0.40 |
| Low-dose SEAE | 9 | 0.74±0.34 | 3.26±0.98 | 1.55±0.68# | 0.89±0.43 |
| Medium-dose SEAE | 9 | 0.65±0.32#,Δ | 2.42±0.54#,Δ | 1.56±0.28#,Δ | 1.01±0.28 |
| High-dose SEAE | 9 | 0.58±0.37#,Δ | 2.09±0.55#,Δ | 1.32±0.71#,Δ | 0.99±0.34 |
| Simvastatin | 8 | 0.65±0.31# | 2.19±0.51# | 1.18±0.79* | 1.32±0.51 |
SEAE: sappanwood ethyl acetate extract; TG: triglycerides; TC: total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol. Data are shown as means ± standard deviations (SD).
P<0.05 vs. blank control;
P<0.05 vs. AS model;
P<0.05 vs. Simvastatin;
P<0.01 vs. blank.