Methods |
RCT |
Participants |
82 university students and staff, mean age 24 years (range 18 to 46), 62% men, 'common cold centre', university department, UK, cough associated with URTI |
Interventions |
Antitussive: codeine phosphate 50 mg as a single dose |
Outcomes |
5‐point subjective rating scale, cough sound pressure levels, cough frequency |
Notes |
No data on adverse effects reported |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Not reported |
Allocation concealment (selection bias) |
Unclear risk |
Not reported |
Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Patients and providers blinded; outcome assessor blinding not reported |
Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Follow‐up not reported |
Selective reporting (reporting bias) |
Unclear risk |
Not reported |
Other bias |
Unclear risk |
No power calculation reported |