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. 2014 Nov 24;2014(11):CD001831. doi: 10.1002/14651858.CD001831.pub5

Freestone 1997.

Methods RCT
Participants 82 university students and staff, mean age 24 years (range 18 to 46), 62% men, 'common cold centre', university department, UK, cough associated with URTI
Interventions Antitussive: codeine phosphate 50 mg as a single dose
Outcomes 5‐point subjective rating scale, cough sound pressure levels, cough frequency
Notes No data on adverse effects reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported
Allocation concealment (selection bias) Unclear risk Not reported
Blinding (performance bias and detection bias) 
 All outcomes Low risk Patients and providers blinded; outcome assessor blinding not reported
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Follow‐up not reported
Selective reporting (reporting bias) Unclear risk Not reported
Other bias Unclear risk No power calculation reported