| Methods |
RCT |
| Participants |
43 children, mean age 3.6 years (range 2 months to 12 years), 58% boys, community private practice, USA, cough due to URTI |
| Interventions |
Other combination: dextromethorphan, guaifenesin and pseudoephedrine (Triaminicol syrup) and dextromethorphan, guaifenesin and pseudoephedrine (Dorcol paediatric cough syrup), treatment frequency and duration unclear |
| Outcomes |
Parent assessment of treatment response |
| Notes |
Adverse effects were not reported |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Not reported |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Patients blinded; blinding of providers and outcome assessors not reported |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Follow‐up not reported |
| Selective reporting (reporting bias) |
Unclear risk |
Not reported |
| Other bias |
High risk |
No power calculation reported. Medication sponsored by medical director of a laboratory who also performed the analysis |
