Table 2.
CACO-2 Assay with the Dual Inhibitor 5
|
Papp (10−6 cm/s) |
|||||
|---|---|---|---|---|---|
| direction | recovery (%) | R1 | R2 | av | efflux ratio |
| A-to-B | 40 | 4.78 | 4.37 | 4.58 | 5.1 |
| B-to-A | 43 | 22.6 | 24.4 | 23.5 | |
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