Figure 3.

Differential expression of TE-derived alternative splice isoforms in tumour versus normal samples. Distributions of the relative expression counts (REC) comparing TE-derived to non-TE-derived alternative splice isoforms in tumour versus normal samples. The formula for REC is described in the Methods and in the electronic supplementary material, figure S6. Data are shown for 13 cancer types and four alternative splice event types. Each dot represents an REC value derived from the average normalized expression counts of the TE- and non-TE-derived isoforms in normal and cancer samples. Higher expression (counts) of the TE-derived isoform in tumour are shown on the right side of the panels, whereas lower expression is shown to the left.