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Pol IV-dependent 21–22 nt siRNAs can cause DNA methylation. (a) Metaplot of average per cent CHH context methylation of Pol IV-DMRs in wt Col and different mutant combinations. (b) Small RNA size distribution of the Pol IV-DMRs shown in (a). (c) Heatmap of CHH DNA methylation at Pol IV-DMRs where each row represents an individual DMR. DMRs are sorted by their methylation level in wt Col Rep A.
