TABLE 1.
A summary of the percent amino acid identity of the human MCT isoforms (matrix was generated using Clustal Omega)
MCT1 | MCT2 | MCT3 | MCT4 | MCT5 | MCT6 | MCT7 | MCT8 | MCT9 | MCT10 | MCT11 | MCT12 | MCT13 | MCT14 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MCT1 | 100 | 59.21 | 39.43 | 44.57 | 24.11 | 29.07 | 29.05 | 22.84 | 23.03 | 24.23 | 28.8 | 29.37 | 30.81 | 24.94 |
MCT2 | 59.21 | 100 | 42.77 | 46.74 | 26.39 | 32.16 | 31.61 | 24.22 | 26.88 | 24.38 | 32.05 | 29.83 | 31.83 | 27.23 |
MCT3 | 39.43 | 42.77 | 100 | 56.93 | 24.71 | 37.5 | 28.12 | 26.34 | 26.46 | 26.61 | 36.05 | 33.47 | 34.44 | 23.98 |
MCT4 | 44.57 | 46.74 | 56.93 | 100 | 25.43 | 36.81 | 31.82 | 26.68 | 28.68 | 26.33 | 32.64 | 34.85 | 30.56 | 27.95 |
MCT5 | 24.11 | 26.39 | 24.71 | 25.43 | 100 | 24.23 | 27.48 | 22.43 | 25.91 | 24.16 | 26.59 | 29.91 | 29.8 | 25.58 |
MCT6 | 29.07 | 32.16 | 37.5 | 36.81 | 24.23 | 100 | 28.57 | 24.19 | 23.94 | 23.81 | 30.32 | 30.18 | 28.43 | 24.71 |
MCT7 | 29.05 | 31.61 | 28.12 | 31.82 | 27.48 | 28.57 | 100 | 21.22 | 26.62 | 20.5 | 25.78 | 25.48 | 34.36 | 22.74 |
MCT8 | 22.84 | 24.22 | 26.34 | 26.68 | 22.43 | 24.19 | 21.22 | 100 | 25.94 | 52.17 | 26.01 | 22.43 | 23.13 | 23.68 |
MCT9 | 23.03 | 26.88 | 26.46 | 28.68 | 25.91 | 23.94 | 26.62 | 25.94 | 100 | 27.23 | 27.47 | 25.68 | 29.24 | 32.16 |
MCT10 | 24.23 | 24.38 | 26.61 | 26.33 | 24.16 | 23.81 | 20.5 | 52.17 | 27.23 | 100 | 25.84 | 23.64 | 24.28 | 26.44 |
MCT11 | 28.8 | 32.05 | 36.05 | 32.64 | 26.59 | 30.32 | 25.78 | 26.01 | 27.47 | 25.84 | 100 | 30.23 | 46.93 | 27.51 |
MCT12 | 29.37 | 29.83 | 33.47 | 34.85 | 29.91 | 30.18 | 25.48 | 22.43 | 25.68 | 23.64 | 30.23 | 100 | 33.01 | 28.57 |
MCT13 | 30.81 | 31.83 | 34.44 | 30.56 | 29.8 | 28.43 | 34.36 | 23.13 | 29.24 | 24.28 | 46.93 | 33.01 | 100 | 26.93 |
MCT14 | 24.94 | 27.23 | 23.98 | 27.95 | 25.58 | 24.71 | 22.74 | 23.68 | 32.16 | 26.44 | 27.51 | 28.57 | 26.93 | 100 |