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. 2020 Jan 24;295(10):3189–3201. doi: 10.1074/jbc.RA119.011546

Table 2.

Degree of sequence conservation (% amino acid identities) within a selection of 13 β-herpesviral core NEC proteins divided into four homology groups

Human CMVsa β-Herpesviruses
Human roseolod
Primate CMVsb Rodent CMVsc
pUL50
    Human CMVs 98.5–99.0 48.0–54.8 30.5–34.9 23.3–24.8
    Primate CMVs 48.0–54.8 47.5–84.1 28.7–41.9 22.8–34.9
    Rodent CMVs 30.5–34.9 28.7–41.9 28.7–50.6 26.1–33.1
    Human roseolo 23.3–24.8 22.8–34.9 26.1–33.1 52.5–94.2
pUL53
    Human CMVs 98.4–99.5 56.6–63.8 32.9–37.4 27.6–31.6
    Primate CMVs 56.6–63.8 55.0–89.9 34.2–45.3 27.6–42.4
    Rodent CMVs 32.9–37.4 34.2–45.3 40.1–61.1 32.7–35.6
    Human roseolo 27.6–31.6 27.6–42.4 32.7–35.6 60.6–97.0

a GenBank accession numbers used were: human CMVs: HCMV strains AD169, P16791, and P16794; Merlin, Q6SW81 and F5HFZ4; TB40, A8T7C7 and A8T7D2; Towne, B9VXL9 and B9VXM2.

b GenBank accession numbers used were: primate CMVs: chimpanzee, Q8QS38 and Q8QS35; rhesus monkey, Q2FAN6 and O71122; simian strain Colburn, G8XTV6 and G8XTV9.

c GenBank accession numbers used were: rodent CMVs: guinea pig strain CIDMTR, U6H6P9 and U6H9V2; murine strain Smith, D3XDN8 and D3XDP1; rat strain Maastricht, Q9DWE0 and Q9DWD7.

d GenBank accession numbers used were: human roseoloviruses: HHV-6A strain Uganda-1102, P52465 and P28865; HHV-6B strain Z29, Q9QJ35 and Q9WT27; HHV-7 strain JI, P52466 and P52361.