Multiple, chimeric origins of ssDNA viruses (and two groups of dsDNA viruses [Papillomaviridae and Polyomaviridae]). The genomes are shown with two colors each, to emphasize the distinct origins of the genes encoding proteins involved in replication (Reps) and those encoding capsid proteins (CPs). JRC, jelly roll capsid protein (nonorthologous JRC genes are shown with different colors); fCP, filamentous capsid protein; pCP, polymorphic capsid protein; DdDp, DNA-directed DNA polymerase; RCRE, rolling-circle replication (initiation) endonuclease; S3H, superfamily 3 helicase. (Adapted from reference 85.)