Table 1.
Genes upregulated and downregulated in the glomeruli of BTBR ob/ob mice
| Symbol | Gene Name | FC | P Value | Aff. ID |
|---|---|---|---|---|
| Top 5 genes upregulated in BTBR ob/ob mice ranked by FC | ||||
| Mmp10 | Matrix metalloproteinase-10 | 32.00 | 1.94E-02 | 120,830 |
| Ccl2/Mcp1 | C-C motif chemokine ligand 2/Monocyte chemoattractant protein-1 | 24.42 | 1.17E-02 | 286,737 |
| Fpr2 | N-formyl peptidase receptor 2 | 22.26 | 2.61E-02 | 288,138 |
| Angpt4 | Angiopoietin-4 | 21.61 | 1.94E-02 | 372,393 |
| Pcdh7 | Protocadherin-7 | 21.31 | 3.46E-02 | 260,740 |
| Top 5 genes downregulated in BTBR ob/ob mice ranked by FC | ||||
| Lypd1 | Ly6/Plaur domain containing 1 | 0.02 | 6.59E-03 | 497,395 |
| Cacna2d2 | Calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.04 | 6.59E-03 | 171,711 |
| Creg2 | Cellular repressor of E1A-stimulated genes 2 | 0.08 | 3.64E-02 | 387,056 |
| Adamdec1 | ADAM-like, decysin 1 | 0.12 | 4.49E-02 | 164,296 |
| Cdx2 | Caudal type homeobox 2 | 0.15 | 2.59E-02 | 177,490 |
FC, fold change; Aff. ID, Affymetrix ID.