Table 2.

Adverse effects

Side Effect	Dietary Sodium Restriction (n=26)	Amiloride/Hydrochlorothiazide (n=26)
Orthostatic hypotension	4 (15)	6 (23)
Gout	0 (0)	1 (4)
Hyponatremia	0 (0)	4 (15)
Hypokalemia	0 (0)	0 (0)
Hyperkalemia	0 (0)	1 (4)
Hyperuricemia	17 (65)	22 (85)

Data are presented as n (%). No significant differences by the McNemar test. Hyponatremia was defined as plasma sodium <136 mmol/L, hypo- and hyperkalemia as plasma potassium <3.5 or >5.5 mmol/L, and hyperuricemia as plasma uric acid >7.1 mg/dl.