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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Endocr Relat Cancer. 2019 Aug;26(8):699–712. doi: 10.1530/ERC-19-0188

Fig. 5. Cell cycle effects with group I PAK inhibition.

Fig. 5.

TPC1, SW1736, and FTC133 were treated with DMSO, 0.5 μM G-5555, or 5 μM FRAX1036 for (A) 24 or (B) 48 hours. Cells were stained with propidium iodide and analyzed by flow cytometry for relative DNA amount. Statistical comparisons were made within each phase of the cell cycle by one-way ANOVA followed by Holm’s procedure. Three biological replicates for each cell line and time point were performed and data are represented as means + SD. ****P ≤ 0.0001, ***P ≤ 0.001, **P ≤ 0.01, *P ≤ 0.05.