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Twenty-four h after I/R injury, brain water content as an index of brain edema was increased. But i.p. MK-4 injection could decrease total brain water content considerably. Data are presented as mean±SEM. *** p < 0.001 compared to control, + p < 0.05 and +++ p < 0.001 compared to I/R+MK4 group (n = 6).
