Table 6. Cut-off value, Youden index, sensitivity, specificity, PPV, and NPV of predictors of in-hospital mortality.

Predictor	Cut-off Value	Youden Index	Sensitivity (%) (95% CI)	Specificity (%) (95% CI)	PPV (%) (95% CI)	NPV (%) (95% CI)
Max lactate at T24 (mmol/L)	3.05	0.418	64.3 (58.2–70.2)	77.4 (73.6–81.0)	58.5 (52.5–64.2)	81.5 (77.8–84.8)
Age (year)	76.5	0.111	30.2 (24.7–36.2)	81.5 (77.9–84.7)	44.6 (37.1–52.3)	70.3 (66.5–73.9)
APACHE III	64.5	0.423	75.2 (69.5–80.3)	67.1 (62.9–71.1)	53.0 (47.7–58.2)	84.6 (80.7–87.9)