Table III.
Gene Ontology Analysis
| Biological Process Category | Genes in Significant List (91 genes) | Genes on Array | p value* |
|---|---|---|---|
| Cell adhesion | 12 | 396 | <0.0001 |
| Regulation of anatomical structure | 6 | 71 | <0.0001 |
| Regulation of locomotion | 5 | 67 | 0.005 |
| Multicellular organismal development | 25 | 1891 | 0.005 |
| Cell motility | 6 | 136 | 0.008 |
| Phosphate transport | 5 | 82 | 0.009 |
| Localization | 24 | 1777 | 0.01 |
| Regulation of cellular component organization and biogenesis | 7 | 207 | 0.01 |
| Regulation of body fluid levels | 5 | 110 | 0.02 |
| Skin development | 2 | 7 | 0.03 |
| Blood coagulation | 4 | 69 | 0.03 |
| Molecular Function Category | Genes in Significant List(91 genes) | Genes on Array | p value* |
| extracellular matrix structural constituent | 10 | 89 | 2.11×10−8 |
| protein binding | 57 | 6680 | 0.0057 |
| structural molecule activity | 13 | 648 | 0.0063 |
| integrin binding | 4 | 43 | 0.0063 |
| glycosaminoglycan binding | 5 | 100 | 0.0127 |
| polysaccharide binding | 5 | 103 | 0.0127 |
| pattern binding | 5 | 114 | 0.0173 |
| heparin binding | 4 | 78 | 0.0304 |
| actin filament binding | 3 | 37 | 0.0304 |
| actin binding | 7 | 284 | 0.0304 |
| cytoskeletal protein binding | 8 | 403 | 0.0495 |
*
p values were derived using a hypergeometric distribution and were subsequently FDR corrected