Table 1. Two-exponential curve fitting results.
| Ipeak | Ito | IK,slow | Iss | |
|---|---|---|---|---|
| WT (n = 24) | ||||
| Τ decay (ms) | – | 185.3 ± 11.0 | 1,115.2 ± 30.5 | – |
| Density (pA/pF) | 41.9 ± 2.9 | 17.0 ± 1.5 | 18.9 ± 1.4 | 5.9 ± 0.3 |
| Percent Ipeak | – | 41 | 45 | 14 |
| LC15 (n = 25) | ||||
| Τ decay (ms) | – | 166.3 ± 6.5 | 1051.8 ± 35.3 | – |
| Density (pA/pF) | 31.5 ± 1.8* | 12.3 ± 1.1* | 13.2 ± 0.9* | 5.9 ± 0.3 |
| Percent Ipeak | – | 39 | 42 | 19 |
Results from fitting a second order exponential equation to the entire decay phase of the potassium current elicited by a 4.5-s depolarization to +40 mV from a holding potential of −70 mV. *, statistically significant.