Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 14;152(2):e201912501. doi: 10.1085/jgp.201912501

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Queralt-Martín et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure S5. — hVDAC3 frequently forms uncharacteristically low-conducting pores with flickering current. Representative current traces obtained with hVDAC3 at −10 and −50 mV applied voltages (gray, lower panel). The ion current flickers between different low-conducting levels and occasionally reaches the level corresponding to the VDAC fully open state of 4 nS. Current records were digitally filtered at 500 Hz using a low-pass Bessel (8-pole) filter. Membranes were formed from DOPC/DOPE/2DOPG. Membrane-bathing solutions consisted of 1 M KCl buffered with 5 mM HEPES at pH 7.4.