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. 2019 Dec 19;152(2):e201912434. doi: 10.1085/jgp.201912434

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© 2019 Gade et al.

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Figure 5. — CaM and FHF modulation of the persistent current is dependent on an intact putative interaction between the III-IV linker and the CTD. Black represents control, red represents addition of CaM overexpression, and blue represents addition of FGF12B overexpression in A and B). (A) Quantified data after overexpression of CaM show failure to rescue persistent currents in R1913H+K1493E. (B) CaM and FHF overexpression failed to rescue persistent currents for mutations on either side of the interaction site after overexpression of CaM and FGF12B. Gray columns with black outline in B represent the control data from WT and mutant channels from Fig. 3. *, P < 0.05.