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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Clin Immunol. 2020 Feb 4;212:108351. doi: 10.1016/j.clim.2020.108351

Figure 3. Roles of NAbs (IgM) during homeostasis and virus infection.

Figure 3.

During homeostasis, NAbs bind to apoptotic cells for phagocytosis, prevent autoimmunity through the binding and clearance of damaged proteins such as double stranded DNA, and aid in the regulation of B-cells. During virus infection, NAbs neutralize viruses, activate the complement system, or recruit the virus to secondary lymphoid organs.