Table 2. Recognition of mucopolysaccharidosis (MPS).
| Clinical features | MPS I | MPS II | MPS III | MPS IV | MPS VI | MPS VII | MPS IX |
|---|---|---|---|---|---|---|---|
| Coarse facial features | + | + | -/+ | -/+ | + | + | -/? |
| Cognitive retardation | -/+ | -/+ | + | - | -/? | + | - |
| Epilepsy | + | + | + | + | + | - | - |
| Hepatosplenomegaly | + | + | + | -/+ | + | + | - |
| Valve disease | + | + | + | + | + | + | - |
| Inguinal and umbilical hernias | + | + | + | + | + | + | - |
| Corneal clouding | + | + | + | + | + | + | - |
| Short stature | + | + | -/? | + | + | + | + |
| Kyphoscoliosis | + | + | + | + | + | + | - |
| Joints stiffness | + | + | -/? | - | + | + | + |
| Hearing loss | + | + | + | + | + | + | -/? |
| Teeth abnormalities | + | + | + | + | + | + | - |
| Enlarged tongue | + | + | + | + | + | + | - |
| Hydrops fetalis | - | - | - | - | - | + | - |
+: positive; -: negative; -/+: normal or positive; -/?: negative but suspicious in some cases.