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. 2020 Mar 9;10:4355. doi: 10.1038/s41598-020-61300-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dasatinib treatment does not affect a tumorigenesis in mice inoculated with EBV-LCLs. NOG mice subcutaneously inoculated Akata-LCLs were treated with dasatinib or vehicle (n = 5). (A) The experimental schema is described. (B,C) Body weight and tumor diameter were measured through the experiments. White circles with a dashed line indicate means of vehicle-treated group, whereas black circles with a solid line indicate those of dasatinib-treated group. The error bars show SD. (D) The tumors removed at the end of the experiment were photographed. The scale bar indicates 10 mm. (E) A total tumor weight at the end of the experiment was analyzed. Statistical analysis was performed using Student’s t test (n.s.: not significant (p ≥ 0.1)).